A U.S. Senate Judiciary Committee hearing on Tuesday has been canceled because of an explosion on a train that killed three people and injured 19 others.

A blast on a Pennsylvania train that occurred just before 9 p.m.

ET on Tuesday killed three and injured nine people, including one critically, and destroyed several cars.

The explosion occurred as the trains were leaving the Union Station in Philadelphia, Pennsylvania, according to The Associated Press.

The Amtrak train carrying the three victims of the explosion, a woman in her 20s and two men in their 30s, was heading to New York City, according in a tweet from the Philadelphia Department of Public Safety.

The woman in the front seat was pronounced dead at the scene, while the other two men were taken to the hospital.

The third passenger, identified as John Fissell, was pronounced deceased at the hospital, Philadelphia Fire Department Capt. Jim Breslow said.

The Pennsylvania State Police bomb squad responded to the scene and found two more bodies on the train, and the third victim was found with life-threatening injuries.

All three were pronounced dead.

The Associated Press identified the victims as:John Fissel, a former student of Harvard Law School; Thomas J. Fissels, a lawyer at Fisler & Johnson; and Steven L. Fissler, a longtime business associate and former business partner of John F. Kennedy Jr.